Norethisterone Enanthate + Estradiol Valerate Injection
- Packing: 1 Ml Ampoule, 1 ml PFS.
- Available Strength : 50 Mg/Ml + 5 Mg/Ml
Description
Product Description: Norethisterone Enanthate + Estradiol Valerate Injection is a hormonal medication combining norethisterone enanthate, a synthetic progestin, and estradiol valerate, a synthetic estrogen. This injectable formulation offers a convenient option for hormone replacement therapy (HRT) in women, providing both estrogen and progestin components in a single injection.
Indications and Usage: Norethisterone Enanthate + Estradiol Valerate Injection is indicated for hormone replacement therapy (HRT) in menopausal and postmenopausal women to alleviate menopausal symptoms, prevent osteoporosis, and manage hormonal imbalances. It is also used as a contraceptive method and in the treatment of certain gynecological conditions.
Dosage and Administration: The dosage of Norethisterone Enanthate + Estradiol Valerate Injection varies depending on the indication, patient's age, and medical history. It is typically administered via intramuscular injection according to a prescribed dosing schedule determined by a healthcare provider. Dosage adjustments may be necessary based on individual patient response.
Dosage Forms and Strengths: Norethisterone Enanthate + Estradiol Valerate Injection is available as a sterile solution in vials or pre-filled syringes. Each milliliter of the solution contains a specific amount of norethisterone enanthate and estradiol valerate, typically ranging from 5 mg/mL to 10 mg/mL for each hormone component.
Contraindications: Norethisterone Enanthate + Estradiol Valerate Injection is contraindicated in pregnant women, women with a history of breast cancer, liver dysfunction, thromboembolic disorders, and hypersensitivity to norethisterone, estradiol, or any of the components of the formulation. It should not be used in women with uncontrolled hypertension or certain cardiovascular conditions.
Warnings and Precautions: Before initiating therapy with Norethisterone Enanthate + Estradiol Valerate Injection, healthcare providers should evaluate patients for cardiovascular risk factors, including hypertension, diabetes, smoking, and obesity. Patients should be monitored regularly for signs of thromboembolic events, breast abnormalities, and other adverse effects associated with estrogen-progestin therapy.
Adverse Reactions/Side Effects: Common adverse reactions associated with Norethisterone Enanthate + Estradiol Valerate Injection include nausea, breast tenderness, headache, breakthrough bleeding, and mood changes. Other potential side effects may include fluid retention, weight gain, and allergic reactions.
Drug Interactions: Norethisterone Enanthate + Estradiol Valerate Injection may interact with other medications, including corticosteroids, anticonvulsants, anticoagulants, and herbal supplements. Healthcare providers should carefully evaluate patients for potential drug interactions before initiating therapy.
Use In Specific Populations Description: Norethisterone Enanthate + Estradiol Valerate Injection is not recommended for use in pregnant women or women who are breastfeeding. It should be used with caution in women with a history of cardiovascular disease, liver dysfunction, or other medical conditions that may increase the risk of adverse effects.
How Supplied/Storage and Handling: Norethisterone Enanthate + Estradiol Valerate Injection is supplied as a sterile solution in vials or pre-filled syringes. It should be stored at controlled room temperature, protected from light and moisture. Unused portions should be discarded according to local regulations for biohazardous waste disposal.