Medroxyprogesterone Acetate Tablets

Description

Introduction: Medroxyprogesterone Injection is a trusted hormonal contraceptive designed to provide safe and effective birth control for women. Manufactured under stringent quality standards, this injectable medication offers a reliable means of family planning, offering peace of mind to individuals seeking contraceptive options.

Indications and Usage: Medroxyprogesterone Injection is indicated for the prevention of pregnancy in women of reproductive age. It provides a convenient, long-acting contraceptive option for those seeking effective birth control.

Dosage and Administration: Administer Medroxyprogesterone Injection as directed by a healthcare professional. Typically, it is injected intramuscularly at intervals of every 3 months (13 weeks). Patients should receive the injection within the first 5 days of a normal menstrual period or within 5 days postpartum if not breastfeeding.

Dosage Forms and Strengths: Medroxyprogesterone Injection is available as a sterile aqueous suspension in single-dose vials containing 150 mg/mL of medroxyprogesterone acetate.

Contraindications: This medication is contraindicated in patients with a known hypersensitivity to medroxyprogesterone acetate or any of its components. It should not be used in patients with a history of thrombosis, liver disease, or certain types of cancers.

Warnings and Precautions: Healthcare providers should counsel patients regarding the risks associated with medroxyprogesterone use, including the potential for bone mineral density loss and thromboembolic disorders. Regular monitoring is advised, especially in patients with a history of depression, diabetes, or hypertension.

Adverse Reactions/Side Effects: Common adverse reactions may include irregular menstrual bleeding, headaches, breast tenderness, and weight changes. Serious adverse events such as thromboembolism and allergic reactions are rare but possible.

Drug Interactions: Medroxyprogesterone Injection may interact with certain medications, including anticonvulsants, antibiotics, and herbal supplements. Healthcare providers should review the patient's medication profile for potential interactions.

Use in Specific Populations Description: Safety and efficacy of Medroxyprogesterone Injection in specific populations such as pregnant or breastfeeding women, adolescents, and geriatric patients have not been established. Consultation with a healthcare provider is essential in these cases.

Clinical Pharmacology: Medroxyprogesterone acetate is a synthetic progestin that inhibits ovulation and thickens cervical mucus, thereby preventing sperm from reaching the egg. It also alters the endometrium, reducing the likelihood of implantation.

Nonclinical Toxicology: Nonclinical studies have demonstrated the reproductive toxicity of medroxyprogesterone acetate at high doses. Animal studies have shown effects on fetal development and fertility.

Clinical Studies: Clinical trials have shown Medroxyprogesterone Injection to be highly effective in preventing pregnancy, with a low failure rate comparable to other long-acting contraceptives.

References: References supporting the safety and efficacy of Medroxyprogesterone Injection are available upon request.

How Supplied/Storage and Handling: Medroxyprogesterone Injection is supplied in single-dose vials and should be stored at controlled room temperature, away from light and moisture. Do not freeze. Discard unused portions appropriately.

Storage and Handling: Store Medroxyprogesterone Injection at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).

Patient Counseling Information: Patients should be counseled on proper administration techniques and potential side effects of Medroxyprogesterone Injection. They should also understand the importance of regular follow-up appointments for monitoring and assessment.

This product description is intended for informational purposes only and should not replace professional medical advice. Patients should consult their healthcare provider for personalized recommendations.