Estradiol Valerate Tablets
- Packing: 1x28 Tablets
- Available Strength : 1 Mg, 2 Mg
Description
Product Description: Estradiol Valerate Tablets are a hormonal medication containing estradiol valerate, a synthetic form of estrogen. These tablets are designed to supplement endogenous estrogen levels in the body and are commonly used in hormone replacement therapy (HRT) to alleviate symptoms of menopause or to treat certain estrogen deficiency conditions.
Indications and Usage: Estradiol Valerate Tablets are indicated for the treatment of moderate to severe symptoms associated with menopause, such as hot flashes, vaginal dryness, and osteoporosis prevention. They are also prescribed for estrogen deficiency conditions, including primary ovarian failure and hypogonadism.
Dosage and Administration: The dosage of Estradiol Valerate Tablets varies depending on the indication and individual patient factors. Generally, the recommended starting dose for menopausal symptoms is 1 to 2 mg daily, with adjustments made based on response and tolerability. For hormone replacement therapy, dosages may range from 1 to 2 mg daily to 2 to 4 mg daily. The tablets are typically taken orally, with or without food.
Dosage Forms and Strengths: Estradiol Valerate Tablets are available in various strengths, including 1 mg, 2 mg, and 4 mg tablets. They come in blister packs or bottles containing a specified number of tablets.
Contraindications: Estradiol Valerate Tablets are contraindicated in patients with a history of estrogen-dependent tumors, undiagnosed abnormal genital bleeding, active thrombophlebitis or thromboembolic disorders, and severe hepatic impairment. They should also not be used during pregnancy or lactation.
Warnings and Precautions: Patients taking Estradiol Valerate Tablets should be monitored closely for potential adverse effects, including an increased risk of cardiovascular events, venous thromboembolism, stroke, and breast cancer. Regular medical check-ups and mammograms may be recommended. Caution should be exercised in patients with a history of hormone-sensitive cancers, liver dysfunction, or gallbladder disease.
Adverse Reactions/Side Effects: Common adverse reactions associated with Estradiol Valerate Tablets may include breast tenderness, nausea, headache, vaginal bleeding or spotting, and fluid retention. Serious adverse effects such as cardiovascular events, thromboembolism, and gallbladder disease are rare but require prompt medical attention.
Drug Interactions: Estradiol Valerate Tablets may interact with certain medications, including rifampicin, barbiturates, phenytoin, and St. John's Wort, potentially reducing their efficacy or increasing the risk of adverse effects. Patients should inform their healthcare provider of all medications they are taking before starting Estradiol Valerate therapy.
Use In Specific Populations Description: Estradiol Valerate Tablets are intended for use in women experiencing menopausal symptoms or estrogen deficiency conditions. They should be used with caution in patients with a history of estrogen-dependent tumors, cardiovascular disease, or liver dysfunction.
How Supplied/Storage and Handling: Estradiol Valerate Tablets are supplied in blister packs or bottles containing a specified number of tablets. They should be stored at room temperature (20°C to 25°C) away from moisture and heat. Unused tablets should be properly disposed of according to local regulations.
